Endocrine Abstracts

This study was designed to determine if prenatal exposure to oleic acid would alter testicular endocrine functions in either an estrogenic or antiandrogenic manner at puberty. Gravid dams were distributed into four groups of five rats each as follows: Control group (1 ml/kg olive oil throughout pregnancy), pre-treatment group (1000 mg/kg of oleic acid for 7 days before mating), preimplantation group (1000 mg/kg of oleic acid for the period of preimplantation), Organogenesis gr...

Heavy metals are present in different waste types and products found in landfills and they are known not only to pose considerable health risk in the waste management sector but also specifically engender health hazards for the environment and people living near the landfills and dumpsites. However, there is little evidence associating male proximity to dumpsites with reproductive function. This study was carried out to examine the effects of heavy metal levels on reproductive...

This study aimed at investigating the effect of high sucrose diet on male reproductive function and if Nigerian honey could exert a protective role. Twenty-four rats were randomly divided into four equal groups of six animals and given water (control); honey (H); high sucrose solution (30%w/v) (HSS); and both high sucrose solution (30%w/v) and honey (HSS+H). Each rat on honey received a daily dose of 10 ml honey/kg per 5 ml of distilled water. Food intake, body weight, organ w...

Genistein is an endocrine-disrupting chemical (EDC), derived from soya, with reported adverse effects on fetal development. The placenta regulates fetal environment for fidelity of organogenesis which can be compromised by several external factors including EDCs. This study examined the influence of genistein on the histomorphometry of the Giant Trophoblast Cells (GTC) of the placenta and the oxidative stress balance across the maternal serum, placenta and t...

Genistein is an endocrine-disrupting chemical (EDC), derived from soya, with reported adverse effects on fetal development. The placenta regulates fetal environment for fidelity of organogenesis which can be compromised by several external factors including EDCs. This study examined the influence of genistein on the histomorphometry of the Giant Trophoblast Cells (GTC) of the placenta and the oxidative stress balance across the maternal serum, placenta and t...